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The global burden of disease attributable to high body mass index in 195 countries and territories, 19902017: an analysis of the Global Burden of Disease Study

Reasonable markers to track: waist circumference, weight, resting heart rate, sleep quality, and a basic liver panel (ALT, AST) before and after long cycles

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It also eases stress while improving mood

There are no other absolute contraindications reported for hydroxocobalamin use in deficiency states, but caution is advised in individuals with conditions such as early Lebers optic neuropathy (a rare hereditary optic atrophy) due to the theoretical risk of worsening vision